Publications

Gene Therapy

Mass spectrometry friendly pH-gradient anion exchange chromatography for the separation of full and empty adeno-associated virus (AAV) capsids

Guapo F, Füssl F, Strasser L, Bones J.

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Gene Therapy

Proteomic Landscape of Adeno-Associated Virus (AAV)-Producing HEK293 Cells

Strasser L, Boi S, Guapo F, Donohue N, Barron N, Rainbow-Fletcher A, Bones J.

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Gene Therapy

SP3-based host cell protein monitoring in AAV-based gene therapy products using LC-MS/MS

Smith J, Strasser L, Guapo F, Milian SG, Snyder RO, Bones J.

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Gene Therapy

Fast and efficient digestion of adeno associated virus (AAV) capsid proteins for liquid chromatography mass spectrometry (LC-MS) based peptide mapping and post translational modification analysis (PTMs)

Guapo F, Strasser L, Millán-Martín S, Anderson I, Bones J.

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Gene Therapy

A Native Mass Spectrometry-Based Assay for Rapid Assessment of the Empty:Full Capsid Ratio in Adeno-Associated Virus Gene Therapy Products

Strasser L, Morgan TE, Guapo F, Füssl F, Forsey D, Anderson I, Bones J.

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